Structure of human Phospholipase D2 catalytic domain

Human PLD structures enable drug design and characterization of isoenzyme selectivity.

hPLD2,Choline phosphatase 2,PLD1C,Phosphatidylcholine-hydrolyzing phospholipase D2

0.2M ammonium sulfate, 20% PEG3350, 0.1M bis-tris pH 6.7

binding site for Di-peptide DTT B 1014 and CYS B 839