Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 1).

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.

HEPES-buffered saline (HBS) with added calcium chloride: 25 mM HEPES, pH 7.4, 150 mM NaCl, 5 mM CaCl

Murine IL-12 in complex with mIL-12Rbeta1-DAPK1 and mIL-12Rbeta2-Calmodulin.

Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1

Interleukin-12 receptor subunit beta-2,Calmodulin-1

IL-12A,Cytotoxic lymphocyte maturation factor 35 kDa subunit,CLMF p35,IL-12 subunit p35

IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40

IL-12 receptor subunit beta-1,IL-12R subunit beta-1,IL-12R-beta-1,IL-12 receptor beta component,DAP kinase 1

IL-12 receptor subunit beta-2,IL-12R subunit beta-2,IL-12R-beta-2,IL-12RB2

mIL-12BC197S-mIL-12Rbeta1D1-D2 crystal structure

Complex, Cytokine, Receptor, SIGNALING PROTEIN