Structure of OHCU decarboxylase from zebrafish

The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.

2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase

20 % (v/v) EtOH, 100mM TrisHCl, pH 8.5, VAPOR DIFFUSION, temperature 277K

OHCU decarboxylase in complex with allantoin

OHCU decarboxylase in complex with guanine

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

The biological unit is a dimer. There are three dimers in the asymmetric unit.

Uric acid, decarboxylation, 5-hydroxyisourate, allantoin, LYASE