Crystal structure of human KRAS P34R mutant in complex with GNP and Phosphate

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER

GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRASP34R.

1.8-2.0 M sodium/potassium phosphate, pH 8.0-8.4

HYDROLASE, small GTPase, signal transduction, GNP binding