Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies.

Adjustable focusing mirrors in K-B geometry

0.2 M magnesium acetate, 20% w/v PEG8000, 0.1 M sodium cacodylate, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K

germline PGT121 light chain, germline PGT121 heavy chain

IgG-fold, anti-HIV antibody precursor, HIV Env gp120, IMMUNE SYSTEM