Crystal Structure of K170M Mutant of Type I 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 in Non-Covalent Complex with Dehydroquinate.

Center for Structural Genomics of Infectious Diseases (CSGID)

1,3,4-TRIHYDROXY-5-OXO-CYCLOHEXANECARBOXYLIC ACID

Insights into the mechanism of type I dehydroquinate dehydratases from structures of reaction intermediates.

Salmonella enterica subsp. enterica serovar Typhimurium

Protein solution: 7.5 mG/mL, 0.25M Sodium chloride, 0.01M Tris pH 8.3, 2mM 3-Dehydroquinic acid (DHR);
Screen solution: Classics F9, 0.05M Potassium phosphate, 20%(w/v) PEG 8000., VAPOR DIFFUSION, SITTING DROP, temperature 295K

Center for Structural Genomics of Infectious Diseases

Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2.

Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 with Citrate Bound to the Active Site.

Crystal Structure of Type I 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 in Covalent Complex with Dehydroquinate.

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
Atomic thermal factors individually refined

Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, LYASE