Caspase-3 tethered to irreversible inhibitor

5-[4-(1-CARBOXYMETHYL-2-OXO-PROPYLCARBAMOYL)-BENZYLSULFAMOYL]-2-HYDROXY-BENZOIC ACID

In situ assembly of enzyme inhibitors using extended tethering.

Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design

Apopain; Cysteine protease CPP32; Yama protein; CPP-32; CASP-3; SREBP cleavage activity 1; SCA-1

Caspase-3, tether, irreversible, inhibitor, APOPTOSIS, HYDROLASE