COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR

Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease

PEG 4000, HEPES, EDTA, Sodium Chloride, Sodium Sulfate, DTT, Spermine_HCl, Glycerol, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K

Residue peptide of the peptidomimetic inhibitor was chemically synthesized.

PROTEASE, PEPTIDOMIMETIC INHIBITOR, INDUCED-FIT, HYDROLASE-HYDROLASE INHIBITOR COMPLEX

BINDING SITE FOR CHAIN E OF PEPTIDOMIMETIC INHIBITOR

BINDING SITE FOR CHAIN F OF PEPTIDOMIMETIC INHIBITOR

BINDING SITE FOR CHAIN G OF PEPTIDOMIMETIC INHIBITOR

BINDING SITE FOR CHAIN H OF PEPTIDOMIMETIC INHIBITOR