Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)prop-1-yn-1-yl)-5-fluorophenethyl)-4-methylpyridin-2-amine

Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.

BNOS,Constitutive NOS,NC-NOS,NOS type I,Neuronal NOS,nNOS,Peptidyl-cysteine S-nitrosylase NOS1

20-24% PEG3350, 0.1M MES
0.14-0.20M AMMONIUM ACETATE,
10% ETHYLENE GLYCOL,
30uM SDS, 5 mM GSH

National Institutes of Health/National Cancer Institute (NIH/NCI)

Nitric oxide synthase, brain (E.C.1.14.13.39)

nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex