Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6

PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER

Assembly of epithelial tight junctions is negatively regulated by Par6

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

A mammalian Par-3-Par-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation

Par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of Par-3

G25K GTP-binding protein, placental isoform

24% PEG 4000, 100mM sodium citrate, 0.2M ammonium acetate, pH 6.4, VAPOR DIFFUSION, HANGING DROP, temperature 293K

semi-CRIB motif, Switch I and II, PDZ domain, GTPase binding domain, SIGNALING PROTEIN