Crystal Structure of RXRa LBD complexed with a synthetic modulator K8012

Sulindac-Derived RXR alpha Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site.

ligand binding domain (UNP residues 223-462)

Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha

20% PEG3330, 0.2M Na Acetate, 100 mM NaCl, 20 mM Tris-Cl, 0.5 mM ligand K-8012, pH 8.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K

Retinoid X receptor-alpha nuclear receptor, Nucleus, SIGNALING PROTEIN