Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.

E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin

Parkin,Parkinson juvenile disease protein 2,Parkinson disease protein 2,Parkin,Parkinson juvenile disease protein 2,Parkinson disease protein 2

100mM Tris pH 8.5, 200mM TMAO, PEG MME 2000

Medical Research Council (United Kingdom)

E3 ubiquitin-protein ligase parkin (E.C.2.3.2.-), Polyubiquitin-B

Complex structure of Parkin and pUB, Transferase, ligase