The structure of the Plasmodium falciparum 20S proteasome in complex with two PA28 activators

The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis.

Sample was a mixture of unbound 20S proteasome, 20S proteasome in complex with one PA28 cap, and 20S proteasome in complex with two PA28 caps.

11S activator of the Plasmodium falciparum proteasome.

Relion autopick from 5 class averages resulting from 200o0 particle picked manually

wait time 0sec
blot time 2sec
blot force -1

National Health and Medical Research Council (NHMRC, Australia)

20S proteasome alpha and beta subunits (E.C.3.4.25.1), Proteasome activator PA28
proteasome, protease, HYDROLASE, 11S subunit, hydrolyse activator, proteasome activator, complex