Reverse polarity of binding pocket suggests different function of a MOP superfamily transporter from Pyrococcus furiosus Vc1 (DSM3638)

Inward-facing conformation of a multidrug resistance MATE family transporter.

10 mg/ml protein, 0.1 M ADA/NaOH, pH 6.5, 10 mM ytterbium chloride, 0.15% w/v OG-Se, 24% w/v PEG2000 MME, VAPOR DIFFUSION, SITTING DROP, temperature 291K

lipid translocase, flippase, membrane protein, TRANSPORT PROTEIN