Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with a UR29 V3 peptide

Conserved structural elements in the V3 crown of HIV-1 gp120.

Bent single Si (111) crystal monochromator (horizontal focusing and deflection) with vertical focusing mirror

Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab light chain

Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab heavy chain

HIV-1 gp120 third variable region (V3) crown

20% PEG 3350, 0.2 M NH4 citrate dibasic, VAPOR DIFFUSION, HANGING DROP, temperature 296K

AUTHORS STATE THAT THE FABS WERE MADE BY ENZYME DIGESTION, THEREFORE THE REAL ENDINGS OF THE CHAINS ARE UNKNOWN.

Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab light chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab heavy chain, HIV-1 gp120 third variable region (V3) crown

human monoclonal antibody, Fab, HIV-1, gp120, third variable loop, antibody-antigen interaction, IMMUNE SYSTEM