Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1907)

Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against Trypanosoma brucei

1.8-2.1 M AMMONIUM SULFATE, 0.2 M
SODIUM CHLORIDE, 0.1 M SODIUM CACODYLATE, PH 6.2-6.8, VAPOR
DIFFUSION, SITTING DROP, TEMPERATURE 298K

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Methionyl-tRNA synthetase, putative (E.C.6.1.1.10)

synthetase, ligase, methionine, inhibitor, Ligase-Ligase Inhibitor complex