Distinct mechanism of MUL1-RING domain simultaneously recruiting E2 enzyme and the substrate p53-TAD domain

MUL1-RING recruits the substrate, p53-TAD as a complex with UBE2D2-UB conjugate.

Mitochondrial ubiquitin ligase activator of NFKB 1

(E3-independent) E2 ubiquitin-conjugating enzyme D2,E2 ubiquitin-conjugating enzyme D2,Ubiquitin carrier protein D2,Ubiquitin-conjugating enzyme E2(17)KB 2,Ubiquitin-conjugating enzyme E2-17 kDa 2,Ubiquitin-protein ligase D2,p53-regulated ubiquitin-conjugating enzyme 1

E3 SUMO-protein ligase MUL1,E3 ubiquitin-protein ligase MUL1,Growth inhibition and death E3 ligase,Mitochondrial-anchored protein ligase,MAPL,Putative NF-kappa-B-activating protein 266,RING finger protein 218,RING-type E3 ubiquitin transferase NFKB 1

UBE2D2, PUBC1, UBC4, UBC5B, UBCH4, UBCH5B

MUL1, C1orf166, GIDE, MAPL, MULAN, RNF218

4% v/v Tacsimate pH 6.0, 12% w/v Polyethylene glycol 3350

MUL1-RING, Ube2d2, STRUCTURAL PROTEIN, TRANSFERASE