Cryo-EM structure of human MCT1 in complex with Basigin-2 in the presence of lactate

Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.

25 mM Tris pH 8.0, 150 mM NaCl, and 0.02% (w/v) GDN

MCT1/Basigin-2 complex in the present of lactate

5F7,Collagenase stimulatory factor,Extracellular matrix metalloproteinase inducer,EMMPRIN,Leukocyte activation antigen M6,OK blood group antigen,Tumor cell-derived collagenase stimulatory factor,TCSF

Cryo-EM structure of human MCT1 in complex with Basigin-2 at 3.6 Angstrom.

Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of BAY-8002

Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of 7ACC2

Cryo-EM structure of the human MCT1(D309N)/Basigin-2 complex

lactate transporter, MCT1, Basigin-2, Proton-coupled monocarboxylate transporter, TRANSPORT PROTEIN