Crystal structure of acetate:succinate CoA transferase (ASCT) from Trypanosoma brucei.

The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei.

Succinyl-CoA:3-ketoacid-coenzyme A transferase

0.05M HEPES-NaOH buffer pH 7.4, 18% (w/v) PEG 3350, 0.35M CaCl2

Japan Agency for Medical Research and Development (AMED)

Ministry of Education, Culture, Sports, Science and Technology (Japan)

Protein crystallized and deposited in this structure is derived from Trypanosoma brucei ILtat 1.4 strain, which is not available at the time of data processing. Database D0A680 is dereived from Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972).

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Succinyl-CoA:3-ketoacid-coenzyme A transferase (E.C.2.8.3.5)

Trypanosoma brucei, acetate:succinate CoA transferase, mitochondrial enzyme, TRANSFERASE