Crystal structure of S. aureus MepR-DNA complex

Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR.

Double-crystal, Si(111) liquid N2 cooled

0.04M Mg Acetate, 0.05M Na Cacodylate, 30% (+/-)-2-methyl-2,4-pentanediol., pH 6, VAPOR DIFFUSION, HANGING DROP, temperature 293K

multidrug resistance, winged helix-turn-helix, transcription repression, mepR operator, TRANSCRIPTION-DNA complex