Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5

Mammalian STE20-like protein kinase 2, MST-2, STE20-like kinase MST2, Serine/threonine-protein kinase Krs-1, Serine/threonine-protein kinase 3 36kDa subunit, MST2/N, Serine/threonine-protein kinase 3 20kDa subunit, MST2/C

0.2 M sodium citrate, 15% (w/v) PEG 3350, 0.1 M HEPES, pH 7.7, vapor diffusion, hanging drop, temperature 277K

Serine/threonine-protein kinase 3 (E.C.2.7.11.1)

Hippo, Mst autoactivation, dimerization, SIGNALING PROTEIN