Structure of Bifidobacterium dentium beta-glucuronidase complexed with C6-hexyl uronic isofagomine

(2~{S},3~{S},4~{R},5~{R})-2-hexyl-4,5-bis(oxidanyl)piperidine-3-carboxylic acid

Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.

Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1)

0.1 M sodium cacodylate, pH 6.5, 8% w/v PEG 20K

Ministry of Science and Technology (Taiwan)

inhibitor, complex, glycosidase, CARBOHYDRATE