Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Clado-C

Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin inhibitor, Cla-B

Structural basis of malaria parasite lysyl-tRNA synthetase inhibition by cladosporin.

THE ENTRY CONTAINS FRIEDEL PAIRS IN I/F_PLUS/MINUS COLUMNS.

0.09M NPS-0.3M Sodium nitrate, 0.3 Sodium phosphate dibasic,0.3M Ammonium sulfate.
1.0M Buffer-pH6.5- Imidazole; MES
monohydrate (acid)
Precipitant Mix-25% v/v MPD; 25% PEG 1000; 25% w/v
PEG 3350

Department of Biotechnology (DBT, India)

Inhibitor, Cladosporin analog, Stereochemistry, PROTEIN BINDING, PROTEIN BINDING-INHIBITOR complex