LSD1-CoREST1 in complex with polymyxin B

Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.

BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2

Programma Giovani Ricercatori Rita Levi-Montalcini 2013

Lysine-specific histone demethylase 1A (E.C.1.-.-.-), REST corepressor 1, Polmyxin B

OXIDOREDUCTASE-REPRESSOR Complex, LSD1, KDM1A, CoREST1, chromatin, epigenetic, oxidoreductase

binding site for residues 6FH C 1 and 4FO C 2

binding site for residues 4FO C 4 and 4FO C 5

binding site for residues 4FO C 5 and DAB C 6

binding site for residues DAB C 9 and DAB C 10