CmlA beta-hydroxylase in chemically reduced diferrous state

A Carboxylate Shift Regulates Dioxygen Activation by the Diiron Nonheme beta-Hydroxylase CmlA upon Binding of a Substrate-Loaded Nonribosomal Peptide Synthetase.

Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

PEG 20000, potassium acetate, HEPES, glycerol

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

4JO0 is this same enzyme in oxidized cluster state

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Oxygen activation, Diiron cluster, Antibiotic biosynthesis, Beta-hydroxylase, METAL BINDING PROTEIN