Crystal Structure of Vat(D) in Complex with Virginiamycin and Coenzyme A

Crystal structure of Vat(D): an acetyltransferase that inactivates streptogramin group A antibiotics.

PEG 400, ethanol, sodium citrate, tris-HCl, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K

STREPTOGRAMIN A ACETYLTRANSFERASE (E.C. 2.3.1.-)

The biological unit is a trimer.
Chains A, B and C form one trimer.
Chains D, E and F form one trimer.

Antibiotic resistance, Acyltransferase, transferase-antibiotic complex