Crystal Structure of PGT 135 Fab in Complex with gp120 Core Protein from HIV-1 Strain JR-FL Bound to CD4 and 17b Fab

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.

Ig-like V-type and C2-type 1 domains (UNP residues 26-208)

20% PEG2000, 0.1 M Tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K

PGT 135 Heavy chain, PGT 135 Light chain, 17b Light chain, 17b Heavy chain, HIV-1 JRFL gp120 core with mini V3 loop, T-cell surface glycoprotein CD4

Immunoglobulin Fold, IMMUNE SYSTEM-VIRAL PROTEIN complex