Crystal structure of GMP reductase C318A from Trypanosoma brucei in complex with guanosine 5'-monophosphate

Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-beta-synthase domain.

Trypanosoma brucei brucei (strain ILTat1.4)

Ministry of Education, Culture, Sports, Science and Technology (Japan)

The source organism of sequence reference UniProtKB entry Q57ZS7 (Q57ZS7_TRYB2), is described as 'Trypanosoma brucei brucei (strain 927/4 GUTat10.1)'. But, in this study, the gene for TbGMPR was isolated from Trypanosoma brucei brucei (strain ILTat1.4). The amino acid sequences of the enzymes from two strains are identical.

Trypanosoma brucei, 5'-monophosphate reductase, guanosine 5'-monophosphate, cystathionine beta synthase motif, OXIDOREDUCTASE