Molecular basis for abrogation of activation of pro-inflammatory cytokines

Structural basis for termination of AIM2-mediated signaling by p202

DNA (5'-D(P*GP*GP*AP*AP*TP*TP*AP*TP*AP*AP*TP*TP*CP*C)-3')

Ifi-202, Interferon-inducible protein p202, Lupus susceptibility protein p202

0.2M calcium acetate, 0.1M Tris-HCl, 20%(w/v) polyethylene glycol 3000, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 289K

AUTHOR STATES THAT THE BIOLOGICAL ASSEMBLY IS UNKNOWN.

OB fold, DNA, DNA BINDING PROTEIN-DNA complex