Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1856)

Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors.

1.8-2.1 M ammonium sulfate, 0.2 M sodium chloride, 0.1 M sodium cacodylate, pH 6.2-6.8, VAPOR DIFFUSION, SITTING DROP, temperature 298K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Methionyl-tRNA synthetase, putative (E.C.6.1.1.10)

synthetase, ligase, methionine, inhibitor, Ligase-Ligase Inhibitor complex