Crystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with DADMe-Imm-A

Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues

0.17 M Sodium Acetate, 25.5% PEG 4000, 0.085 M TrisHCL, 15% Glycerol, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K

The same protein with ImmA and PO4 in the active site

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

purine nucleoside phosphorylase (E.C.2.4.2.1)

The asymmetric unit contains the functional hexameric unit

purine nucleoside phosphorylase, Transferase