Structure of ATP citrate lyase from Methanothrix soehngenii in complex with citrate and coenzyme A

Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.

ACL-A subunit of the heteromeric ACL-A/B ATP citrate lyase

ACL-B subunit of the heteromeric ACL-A/B ATP citrate lyase
Succinyl-CoA ligase (ADP-forming) subunit alpha

14% PEG3350
4% tacsimate pH 8.0

Protein sample buffer:
20 mM citrate pH 6.0, 150 mM NaCl
10 mM CoASH

Citrate lyase, subunit 1 (E.C.2.3.3.8), Succinyl-CoA ligase (ADP-forming) subunit alpha (E.C.6.2.1.5)

ATP citrate lyase, central metabolism, acetyl-Coa, citrate shuttle, rTCA cycle, citryl-CoA, lipogenesis, LYASE