Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 2

Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants.

0.2 M NA,K L-TARTRATE, 21% (W/V) PEG3350

Epigenetics, Histone deacetylase, HDAC8, Selective inhibitor, Pathogen, hydrolase