M1prime peptide from IgE bound by humanized antibody 47H4 Fab

Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice.

PEG 3350, 0.2 M Ammonium sulfate, pH 5.7, VAPOR DIFFUSION, SITTING DROP, temperature 300K

Residues numbered 9-43 are from the GENBANK accession AAB20659

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Fab h47H4 light chain, Fab h47H4 heavy chain, M1prime-derived peptide