Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.

IgG-binding protein A, Staphylococcal protein A

20% PEG 3350, 25 mM NaCl, 50 mM Hepes, pH 7.2, VAPOR DIFFUSION, HANGING DROP, temperature 293K

Trastuzumab light chain, Trastuzumab heavy chain, Immunoglobulin G-binding protein A, Protein L fragment

monoclonal antibody, immune system, cancer therapeutic