Crystal structure of family II Inorganic pyrophosphatase in complex with PNP

A trimetal site and substrate distortion in a family II inorganic pyrophosphatase

Manganese-dependent inorganic pyrophosphatase

Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase

100mM HEPES/K+ (pH 7.5), 2.3-2.5M ammonium sulphate, 3-4% PEG 400, VAPOR DIFFUSION, SITTING DROP, temperature 277K

(2PN 2001, SO4 4003), (2PN 2002, SO4 4004) ARE IN ALTERNATE CONFORMATIONS OF EACH OTHER.

Manganese-dependent inorganic pyrophosphatase (E.C.3.6.1.1)

pyrophosphatase, substrate complex, HYDROLASE