Type VI secretion system effector RhsP in its post-autoproteolysis and dimeric form

Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP.

Type VI secretion system effector RhsP in its post-autoproteolysis form

Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)

In cleaved RhsP, the cleavage at F1131/L1132 allows the VIR to re-position itself in a U-shape manner with both the N and C termini located at the lid region.

C-terminal peptide from Putative Rhs-family protein

National Natural Science Foundation of China (NSFC)

T6SS, Rhs proteins, polymorphic toxins, TOXIN