Structure of GluK2-LBD in complex with GluAzo

(4R)-4-[(2E)-3-{4-[(E)-phenyldiazenyl]phenyl}prop-2-en-1-yl]-L-glutamic acid

A photoswitchable neurotransmitter analogue bound to its receptor.

Glutamate receptor, ionotropic kainate 2

2.05 M lithium sulfate, 10 mM magnesium chloride, 50 mM MES sodium, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K

PROTEIN COMPRISES RESIDUES 429-544 AND RESIDUES 667-806 OF UNP P42260 SEPARATED BY A GT LINKER.

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : WITH TLS ADDED

membrane protein, glycoprotein, transmembrane protein, ligand-binding domain, ion transport, ion channel, ionotropic glutamate receptor, kainate receptor, GluAzo, PCL, photochromic ligand, MES, synapse, presynaptic cell membrane, postsynaptic cell membrane, SIGNALING PROTEIN