STRUCTURE OF POLYAMINE OXIDASE IN THE REDUCED STATE

Structural Bases for Inhibitor Binding and Catalysis in Polyamine Oxidase

THR C 386 HAS WRONG CHIRALITY AT ATOM CB

A 30 ANGSTROM U-SHAPED CATALYTIC TUNNEL IN THE CRYSTAL STRUCTURE OF POLYAMINE OXIDASE

STRUCTURE OF POLYAMINE OXIDASE IN COMPLEX WITH GUAZATINE

STRUCTURE OF POLYAMINE OXIDASE IN COMPLEX WITH 1,8-DIAMINOOCTANE

COVALENT ADDUCT BETWEEN POLYAMINE OXIDASE AND N1ETHYLN11((CYCLOHEPTYL)METHYL)4, 8DIAZAUNDECANE AT PH 4.6

COVALENT ADDUCT BETWEEN POLYAMINE OXIDASE AND N1ETHYLN11((CYCLOHEPTYL)METHYL)4, 8DIAZAUNDECANE AT PH 7.0

CATALYSES THE OXIDATION OF THE SECONDARY AMINO GROUP OF POLYAMINES (SPERMINE, SPERMIDINE AND THEIR ACETYL DERIVATIVES) THIS IS IMPORTANT FOR REGULATION OF POLYAMINE INTRACELLULAR CONCENTRATION.

IN THE CRYSTAL WHILE THE CHAIN C FORMS A
HOMODIMERWITH A SYMMETRY RELATED MOLECULE. THE
PROTEIN ISACTIVE AS A MONOMER.

FLAVIN-DEPENDENT AMINE OXIDASE, OXIDOREDUCTASE