Crystal structure of serine hydroxymethyltransferase from Mycobacterium tuberculosis

Seattle Structural Genomics Center for Infectious Disease (SSGCID)

(2S)-2-amino-6-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]hexanoic acid

Increasing the structural coverage of tuberculosis drug targets.

Single crystal, cylindrically bent, Si(220)

HAMPTON INDEX, G12: 25% PEG 3350, 200MM MGCL2, 100MM HEPES, MYTUD.00783.A AT 20 MG/ML, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 290K

Seattle Structural Genomics Center for Infectious Disease

pdb entry 2dkj modified by ccp4 program chainsaw

Serine hydroxymethyltransferase 1 (E.C.2.1.2.1)

MYCOBACTERIUM TUBERCULOSIS, serine hydroxymethyltransferase, One-carbon metabolism, Pyridoxal phosphate, Transferase, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, SSGCID