PanDDA analysis group deposition of ground-state model of PTP1B, using pre-clustering, cluster15

PanDDA analysis group deposition of ground-state model

Tyrosine-protein phosphatase non-receptor type 1

0.3 M magnesium acetate, 0.1 M HEPES pH 7.5, 0.1% beta-mercaptoethanol, 13-14% PEG 8000, 2% ethanol

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

Reanalysis of original XChem crystallographic fragment screen of PTP1B

PanDDA, Diamond I04-1 fragment screening, protein tyrosine phosphatase, PTP, protein tyrosine phosphatase 1B, PTP1B, enzyme, allostery, multiconformer, HYDROLASE