Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with MAT-POS-e119ab4f-5 (Mpro-P2358)

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors

3CL-PRO, 3CLp, Main protease, Mpro, Non-structural protein 5, nsp5, SARS coronavirus main proteinase

Severe acute respiratory syndrome coronavirus 2

SARS-CoV-2 main protease screened against COVID Moonshot compounds by X-ray Crystallography at the XChem facility of Diamond Light Source beamline I04-1
Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot

Diamond Light Source, I04-1, COVID Moonshot, CMD, Mpro, fragment screening, PanDDA, XChemExplorer, VIRAL PROTEIN