Crystal Structure of the RA and PH domains of Lamellipodin

Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling.

Ras-associated and pleckstrin homology domains-containing protein 1

RAPH1, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein, Lamellipodin, Proline-rich EVH1 ligand 2, PREL-2, Protein RMO1

RAPH1, ALS2CR18, ALS2CR9, KIAA1681, LPD, PREL2, RMO1

200 mM sodium malonate pH 5.0, 20% (w/v) polyethylene glycol 3350, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K

The same protein but encompass the coiled-coil, RA and PH domains

HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT

RA-PH, coiled-coil region, Ras-association domain, pleckstrin homology domain, cytoskeletal protein, Ena/VASP binding, cell migration, cell adhesion, SIGNALING PROTEIN