Crystal structure of hMTH1 N33G in complex with LW14 in the presence of acetate

2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1

crystallized in: 23-27% PEG3350, 0.2 M LiSO4, 0.1 M sodium acetate pH 4.5

soaked in: 27% PEG3350, 0.2 M LiSO4, 0.1 M sodium acetate pH 4.5, 20% DMSO, 10 mM compound

7,8-dihydro-8-oxoguanine triphosphatase (E.C.3.6.1.55,3.6.1.56)

Inhibitor, Complex, Hydrolase, DNA repair, Fragment