Design and Preparation of Potent, Non-Peptidic, Bioavailable Renin Inhibitors

Design and Preparation of Potent, Nonpeptidic, Bioavailable Renin Inhibitors

25-30% PEG 4000, 0.6M NaCl, 0.1M Citrate(pH 4-5), VAPOR DIFFUSION, SITTING DROP, temperature 293K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

human renin, Aspartyl protease, Cleavage on pair of basic residues, Disease mutation, Glycoprotein, Hydrolase, Membrane, Protease, Secreted, Zymogen