Crystal structure of anti-IL-13 antibody CNTO607

Epitope mapping of anti-interleukin-13 neutralizing antibody CNTO607.

0.1 M CAPS pH 10.4, 18% PEG 3350, 3% MPD, VAPOR DIFFUSION, HANGING DROP, temperature 293K

Crystal structure of the complex between CNTO607 Fab and IL-13

FAB WAS OBTAINED BY PAPAIN CLEAVAGE OF ANTIBODY.

CNTO607 Fab Light chain, CNTO607 Fab Heavy chain

IL-13, antibody, Fab, MONOCLONAL ANTIBODY, IMMUNE SYSTEM