Crystal Structure of Cathepsin-G and Neutrophil Elastase Inhibited by S. aureus EapH2 at pH 8.5

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2.

C-terminal truncation (UNP residues 21-243)

Bone marrow serine protease,Elastase-2,Human leukocyte elastase,HLE,Medullasin,PMN elastase

Staphylococcus aureus subsp. aureus Mu50

0.1 M Tris, 0.2 M magnesium chloride, 25% PEG3350

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

Protease Inhibitor, Immune Evasion, Neutrophil, S. aureus, HYDROLASE-INHIBITOR complex