X-ray structure of PI3Kinase Gamma in complex with Copanlisib

Discovery and Sar of Novel 2,3-Dihydroimidazo(1,2-C)Quinazoline Pi3K Inhibitors: Identification of Copanlisib (Bay 80-6946)

PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM
CATALYTIC SUBUNIT GAMMA, RESIDUES 144-1102

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.

PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM (E.C.2.7.1.137, 2.7.1.153)