CryoEM structure of the MDA5-dsRNA filament with 87-degree helical twist

Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.

DExD/H-box helicase consisting of Hel1, Hel2, Hel2i, and pincer domains, followed by a C-terminal domain

Double-stranded RNA from bacteriophage Phi6

Filament samples were diluted twofold from 0.8 mg/ml to 0.4 mg/ml immediately prior to plunge freezing

Interferon-induced helicase C domain-containing protein 1

RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3')

RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3')

Helicase with 2 CARD domains,Helicard,Interferon induced with helicase C domain protein 1,Melanoma differentiation-associated protein 5,MDA-5,RIG-I-like receptor 2,RLR-2

MDA5-dsRNA filament with 74-degree twist and bound to AMPPNP

Interferon-induced helicase C domain-containing protein 1/RNA Complex

The biological assembly is a helical filament

Protein-RNA complex, helical filament, ATPase, innate immune receptor, IMMUNE SYSTEM