Catalytic domain of the human E3 ubiquitin-protein ligase HUWE1

HECT, UBA and WWE domain-containing protein 1, Upstream regulatory element-binding protein 1, URE-binding protein 1, URE-B1, Mcl-1 ubiquitin ligase E3, Mule, ARF-binding protein 1, ARF-BP1, Large structure of UREB1, LASU1, Homologous to E6AP carboxyl terminus homologous protein 9, HectH9

HSPC272, HUWE1, KIAA0312, KIAA1578, UREB1

15% PEG-4000, 10% ISOPROPANOL, 0.1 M TRIS BUFFER, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. ATOM RECORD CONTAINS SUM OF TLS AND RESIDUAL B FACTORS. ANISOU RECORD CONTAINS SUM OF TLS AND RESIDUAL U FACTORS

E3 ubiquitin-protein ligase HUWE1 (E.C.6.3.2.-)

ALPHA AND BETA PROTEIN (A + B), E3 LIGASE, HECT DOMAIN, UBL-CONJUGATION PATHWAY, Alternative splicing, Chromosomal rearrangement, Cytoplasm, Differentiation, Disease mutation, DNA-binding, Ligase, Mental retardation, Nucleus, Phosphoprotein, Ubl conjugation pathway, Structural Genomics, Structural Genomics Consortium, SGC